?????????? ???? ???? ???? ??????? ??? ???????????? ??? ??? ????????? ??????? ??? ????? ???? ??????????? ???? ??? ????????? ???????. ??? ??? ??????????? ?????, ??? ?????????? ??? ????????? ????? ?????????? ????? ???????????. ?? ??? ???????? ???????? ??? ??????????? ???? ?? FDA ??? 1998. ?? ??? ????? ?????? ??? ??? ?????????????? ???????? ????? ???? ?????????, ??? ?? ????????? ???? ?? ?????????????? ??? ?????????? ??? ??? ????. ?? ??? ????? ????????? ???? ?????????? ??? ???????. ??? ?????, ?????????? ????? ???? ?????? ???? ??????? ????????? ??? ??? ???????? ?? ???? ??? ??????? ????? ????? ??????????? ???? ???? ????????? ??? ?? ?????????? ??? ???????????????? ???? ?? ??? ?????????? ??? ????, ??? ?????? ???????? ??? ?????-??????? ?????. ??????? ???? ???? ????? ??????? ??? ?????????? ??? ????? ????? ?????-?????? ???????????? ??? ?????? ?????? ??????? ???? ????? ??? ????????? ???? ???????. ?????-?????? ????????????? ?????????? ???? ???????????? ????????? ???????????? ????? ??????? ??? ?????????? ??? ???? ???? ?????????? ?????????? ???? ?????????? ??????. ???? ?????-?????? ????????? ????????????? ???????, ???? ?? ??. ??. FDA ?????????? ??? ?? ??? ?? GRAS (?????????) ????? ????????.

?????????? ??? ????? ?????? ???????? ??? ????? 400 ????? ???, ?????????????? ???????????? ??????????, ????????????? ??????????, ????????????? ????? ??? ??????, ???????????? ????????? ??? ????????, ????????????, ??????, ???? ????, ???? ??????????, ??????? ????????, ??? ?????? ?????????. ???????-????????? ?????????? ????? ??? ??????? ????? ????? ????????? ?????????, ??? 87 ??????? ?????????? ??? ?? ???????????? ?????? ??????. ?????? ?????? ??? ?????????? ????? ???????????? ??????? ???????-????????? ?????????? ???? ?????????? ??? ?? ????????, ????? ???? ???? ??? ?????? ??? ???????? ????? ????????. ???? ???? ??????? ????? ??????????? ?? ????????? ????? ?????????? ??? ??? ?????.