???? ??? ?? ????????? ???????????????? ?????? ??? ?? ????????????????????? ??? ?????????

???? ????????????? ??????????????, ????? ????? ?????????? ???????? ?? ????????????? ??? ???????-positive ?????????? ??? ??????????????, ??? ??? ?? ?????? ???????????? ???????? ???? ????????????? ????????? ??? ???????. ?? ????? ???? ??????? ?????? ??? ?????????, ?????????? ??? ?????? ??????.

????????? ?????

????????? ????????

????????????

???? ??? ?? ????????? ???????????????? ?????? ??? ?? ????????????????????? ??? ?????????. NISIN ??? ?? ????????? ????????? ??????? ??? ?? ?????????????? ??? ?? ????????? ??? Lactococcus lactis subsp. ??????? (???-????). ????? ??? ?? ????????? ????????????, ????????? ???? ?? ??.??. (????????? ????????? ????? E-234), ??????? ???? ?? ????? ????? ??? ?????-positive ??????????, ???????? ??????-???????? ?????????? ????? ??? ???????????? ???????, ???????????????? ???????, ????????? ????????????????, ????????? ????????, ???"? ?.

????????????2

????????????????

????? ??? ????????? ????? ???? ??? ???? ??? ????? 50 ?????? ??? ??? ????????????? ??? ?? ??????????????? ??? ?????????? ???? ??? ????? ?????? ?????????? ????? ??? ???????? ??? ????????? ??? ??? ??????? ???? (??????????? ????????????? ??? ???????? ????????? 1995).

????? ??? ?????? ??? ?? ????? ?????????????? ??? ????????: ?????? ??????????, ?????, ????? ???????? ??? ????? ????????? ????, ???? ??? ?? ??????????, ??????, ????? ????, ???"? ?. ????? ????, ???"? ?.

????? ??? ???????? ??? ?? ????? ???? ??? ????????? ?????????? ????? ?? ????? ? ???? (3.5-8.0), ??????????????: ????????? ??? ??? ??? ???????, ???? ???, ?????? ???, ?????? ??????????? ???? ???, ??????????? ???????? ???; ???? ?????????? ????? ??? ?????????, ??????, ???????, ????? ????, ???"? ?; ?????? ??? ???-?????? ??????, ???"? ?. ?????? ??? ???-?????? ??????, ????????, ??????????? ??? ????????? ?????; ????? ??? ????? ??????????????? ?????????????? ??????, ????????????? ????? ????????, ????? ????????? ?????? ??????? ??? ?????????? ????; ????? ??? ??????; ????????????? ?????? ?? ??????????; ??????? ? ?????? ??? ????????? ?????????????? ????????? ??? ??????? ????????; ????????????? ????? ??? ??????; ????? ??????????????; ????????? ?????; ???? ????? ??? ?????????? ????? ??? ??????????; ?????????????? ??????????? ??? ?????????? ????? ??? ???.

?????? ??? ???? ??????????????? ????????? ???? ????????? 95/2/EC ??? ?? ????????? ?????? ????? ?????? ??? ?? ??? ?????. ?????? ?? ??.??., ???? ?????????? ?????? ??? ???? ????????? ?????????????? ?????? ????, ?????? ???????????? ??????? ?????? ??? ????? ?? ?????.

????????? ????????????

????????? (???? ?? ???? ????)	≥ 1000 IU/mg	???? (???)	≤1 ????????	????? ?????
????????		???????? (???)	≤1 ????????	?????????????	????? ??? 25 ?
? (5% ??? ????????? ???????)	3.10-3.60	??????????? (??)	≤1 ????????	E. ?????	????? ??? 25 ?
???????	?? ???? ????? ??????	??????? ????????	≥ 50.0%	????????????	??????