Ni aaye ti iwadii ilera inu inu, Polydextrose ti p? ni ipin bi okun ij??mu ti omi ti o w?p?. Bib??k?, ?p?l?p? aw?n ijinl? a?ey?ri ni aw?n ?dun aip? ti fihan pe moleku sintetiki laileto polymerized lati glukosi j? “orin pup?” ti o ?e atunto microecology inu ifun nipas? ?na m?tta ti “ilana iki agbara agbara - ifunni deede ti microbiota - i?esi kasikedi metabolite”. Iwadi tuntun ni Iseda Gastroenterology ni ?dun 2024 t?ka pe gbigbemi ojoojum? ti 10-15g ti polyglucose le mu iduro?in?in ti idena ifun p? si nipas? 37% ati dinku ipele ti ifosiwewe iredodo IL-6 nipas? 29%. Awari yii kii ?e iyipada im?-ibile nikan ?ugb?n o tun funni ni igbega si igbi ohun elo ibawi kan ti o wa lati ile-i?? ounj? si oogun ile-iwosan.

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Youdaoplaceholder0 Abala 1 Im? Iyipada Iyipada: “Gbogbo im?ye apa ounj? ounj?” ti moleku kan

Youdaoplaceholder0 1.1 Idibaj? viscosity: “Idahun oye” lati inu si olu?afihan

Iyat? ti polydextrose wa ninu iyipada viscosity idahun Ph-re:

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Youdaoplaceholder0 ìy?nu ? (pH 1.5-3.0): Aw?n ?w?n molikula j? ?na asop? agbelebu nipas? aw?n ifunm? hydrogen lati ?e agbekal? eto n?tiw??ki onis?po m?ta, aw?n ??? viscosity to 1500 mPa·s, fa fifal? o?uw?n ofo inu inu nipas? to 45% lasan (fiwera p?lu 20% ti ounj? pataki)

Youdaoplaceholder0 Kekere ifun ? (pH 6.0-7.4): Aw?n asop? hydrogen ti baj? ni apakan, iki dinku si 400 mPa·s, ati adsorption bile acid dinku gbigba idaabobo aw? nipas? 18% laisi ni ipa lori gbigba ounj?;

Youdaoplaceholder0 Colon ? (pH 7.0-7.5): Bakteria makirobia ti b?r?, viscosity disintegrates si isal? 50 mPa·s, kukuru-pq ?ra acids (SCFAs) ti wa ni idasil?, p?lu butyric acid if?kansi nipa 3.2 igba, titun?e taara ifun epitheliure cell.

Youdaoplaceholder0 Im?-?r? Breakthrough: Im?-?r? DSM's SmartVisc? le ?e akan?e aw?n iyipo viscosity fun aw?n apakan ori?iri?i nipas? ?i?atun?e iw?n ti polymerization (iye DP), g?g?bi agbekal? G-iru ti a ?e pataki fun aw?n alaisan ti o ni is?d?tun gastroesophageal, eyiti o ?e fiimu aabo ti ara p?lu iki ti o to 2000 m.

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Youdaoplaceholder0 1.2 Ilana Microbiota: Lati “fifun ifunni-pup?” si “ere ti a fojusi” ?

Aw?n prebiotics ti a?a nigbagbogbo n ?e aibikita gbogbo microbiota, lakoko ti polydextrose ?e afihan aw?n agbara ilana to peye:

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Youdaoplaceholder0 Inhibition Upstream : Ipo viscosity giga n ?e idena ti ara ni olu?afihan isunm?, idinam? ifaram? ti aw?n kokoro arun pathogenic (bii Escherichia coli), dinku o?uw?n imunisin pathogen nipas? 52%;

Youdaoplaceholder0 Il?siwaju ibosile ? : Aw?n aj?kù Oligosaccharides ni a f?f? lo nipas? aw?n kokoro arun ti o ni anfani g?g?bi Bifidobacterium ati Roseella, ati pe opo w?n p? nipas? 68% l?hin ?s? m?j? ti ilowosi (da lori ilana ilana metagenomic);

Youdaoplaceholder0 Metabolic Amu?i??p? : Butyric acid ti a ?e mu ki olugba GPR109A ?i??, nfa iyat? s??li T ilana ilana, ati pe o mu it?ka iw?ntunw?nsi aj?sara ifun p? si 0.91 (ilana ilera> 0.85).

Youdaoplaceholder0 Abala 2 Iji Ohun elo: I?e Aala-aala lati Tabili si Bed Ile-iwosan

Youdaoplaceholder0 2.1 Ile-i?? Ounj?: “?njini alaihan” p?lu aw?n i?? i?agbega

Youdaoplaceholder0 Iyika Iyika: ?gb? Meiji ti Japan ti ?e agbekal? aw?n kuki-sucrose odo nipa lilo anfani ti agbara mimu omi (8.3g omi / g) ati iduro?in?in gbona (ifarada si 220 ° C) ti polyglucose, idinku aw?n iyipada glukosi ?j? postprandial nipas? 41%.

Youdaoplaceholder0 Ohun mimu Innovation : Nongfu Spring 's Intestinal Sparkling Water, eyi ti o nlo aw?n colonic bakteria gaasi-producing ohun ini ti polyglucose lati ran l?w? àìrígb?yà lai híhún, ta lori 8 million igo ni aw?n oniwe-ak?k? osu lori oja;

Youdaoplaceholder0 A?ey?ri Rir?po Ounj?: Soylent ni AM?RIKA nlo ilana iki-giradient lati fa igba itusil? agbara l? si aw?n wakati 6 ati il?siwaju ifarada ti aw?n a?aju-ije Ere-ije gigun nipas? 23%.

Youdaoplaceholder0 2.2 Ounj? ile-iwosan: “Asà idena ifun” fun aw?n alaisan ICU

Iwadi RCT ti Sir Run Run Shaw Hospital, Ile-iwe ti Oogun, Ile-?k? giga Zhejiang (n=204) fihan pe:

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Youdaoplaceholder0 Idena ikolu : Ninu aw?n alaisan ICU ti o ni afikun p?lu 15g ti polydextrose lojoojum?, i??l? ti sepsis enterogenous dinku nipas? 44%;

Youdaoplaceholder0 Atunse Mucosal : Plasma ligonin (aami kan ti permeability ifun) aw?n ipele dinku nipas? 31% ati iwuwo s??li goblet p? si nipas? 39%;

Youdaoplaceholder0 Immunomodulatory : Idojuk? Serum IgA p? si nipas? 28%, ati pe ipin s??li CD4+/CD8+ pada si iw?n deede.

Youdaoplaceholder0 Orí 3 Iyika Im?-?r?: Lati Ap?r? Molecular si Ounj? It?kasi I?eduro AI

Youdaoplaceholder0 3.1 Atunse igbekale: ?ii is?di lori ibeere

Youdaoplaceholder0 Ifojusi viscosity : Nipa i?afihan aw?n ?w?n ?gb? sorbitol, polyglucose kan pato ti o tuka (iru C) ti ni idagbasoke, ti iki r? sil? ni kiakia si 10 mPa·s ni pH 7.0, pataki fun aw?n eniyan ti o ni àìrígb?yà;

Youdaoplaceholder0 Asa Imudara : Roguet, Faranse, ?e agbekal? im?-?r? Probiocoat? microcapsule ti o ?e agbekal? aw?n probiotics ni matrix polyglucose kan, jij? o?uw?n iwalaaye acid inu inu lati 15% si 92%.

Youdaoplaceholder0 3.2 IT?R? Orík?: Lil? koodu ti idasi ara ?ni ?

Eto “Twin Digital ti ifun” ti a ?e nipas? NutriAI, ile-i?? Israeli kan, ?ep? aw?n ?ran 200,000 ti data ododo ododo eniyan ati aw?n awo?e agbara ito, eyiti o le ?e as?t?l? esi ?ni k??kan si polydextrose:

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Youdaoplaceholder0 Imudara iw?n lilo: 8-12g / ?j? + fructooligosaccharides ilana apap? ti a ?e i?eduro fun aw?n alaisan IBS dinku is?l? ti ipal?l? inu nipas? 67%;

Youdaoplaceholder0 Scene fit : Ilana ada?e ti o ni agbara giga ti a ?e fun aw?n elere idaraya, eyiti o mu iw?n bakteria colonic p? si nipas? 40% ati yago fun aibal? nipa ikun lakoko ik?k?.

Youdaoplaceholder0 \ n \ n Abala K?rin: Idarudap? Ile-i??: Agbara Im?-?r? Lab? Aw?n ?ja Trillion-dola ?

Youdaoplaceholder0 4.1 Ije Agbara: Aw?n ile-i?? Kannada ti bori lori ohun ti t?

Youdaoplaceholder0 Baolingbao Bio : ?e idoko-owo 800 milionu yuan lati k? ipil? i?el?p? polyglucose ti o tobi jul? ni agbaye, im?-?r? synthesis enzymatic lati ?a?ey?ri mim? 99.9%;

Youdaoplaceholder0 Hualixi Biotech ? : Idagbasoke nano-fibrotic polyglucose, ifam? ilana viscosity p? nipas? 4 igba, gba NMPA Special Medical ounje if?w?si;

Youdaoplaceholder0 Ifilel? Transnational : DuPont n ?e ifowosowopo p?lu Ile-iwosan Mayo lati ?e ilosiwaju idanwo ile-iwosan Ipele III ti polydextrose ni idena ti akàn colorectal.

Youdaoplaceholder0 4.2 Aw?n italaya Im?: Aafo lati Laabu si ?ja Mass

Pelu ?ri ijinle sayensi ti o to, iwadi olumulo fihan pe:

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Youdaoplaceholder0 Aami af?ju Im?: Nikan 31% ti gbogbo eniyan loye aw?n iyat? i?? ?i?e laarin polydextrose ati aw?n okun ti o w?p?;

Youdaoplaceholder0 Aw?n aburu iw?n lilo : 45% ti aw?n onibara gbagb? ni a?i?e pe "di? sii dara jul?", eyiti o le fa idamu bii bloating;

Idahun Ile-i?? Youdaoplaceholder0 : Awuj? Ounj? Kannada ti tu Iwe funfun sil? lori Ohun elo ti Polydextrose, tito ipil? ailewu ti 15g fun ?j? kan.

Youdaoplaceholder0 Chapter 5 Iran ojo iwaju: Tuntumo Fibre's 'Ala Smart' ?

Youdaoplaceholder0 5.1 Brain-Gut Axis Breakthrough: Afara Molecular kan lati inu ikun si ?dun

Aw?n adanwo ?ranko tuntun ni Ile-?k? Im?-?r? ti California ti rii:

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Youdaoplaceholder0 iderun aniyan : Aw?n eku ninu ?gb? ilowosi polyglucose p? si akoko iwadii w?n ni idanwo iruniloju nipas? 53%;

Youdaoplaceholder0 Mechanism wiwa: Butyric acid mu ikosile BDNF ?i?? ninu hippocampus nipas? idena-?p?l? ?j?, jij? iwuwo synapti nipas? 29%.

Youdaoplaceholder0 5.2 Isedale Sintetiki: 'F??mu Gb?hin' ti aw?n okun ti a ?e eto

Ile-i?? Ginkgo Bioworks ni Am?rika ti ?e atun?e aw?n igara iwukara nipa lilo im?-?r? CRISPR-Cas9 lati ?e ik?k? taara “polydextrose-pipade-pil???” p?lu aw?n i?? adani:

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Youdaoplaceholder0 Precise ìf?kànsí ? : O le pataki jeki idagba ti Achaemenia, ati aw?n oniwe-?p?l?p? ti wa ni p? nipa 80% ni isanraju si dede;

Youdaoplaceholder0 Idahun Smart ?: sens? pH ti a ?e sinu, i?edede iyipada viscosity ni il?siwaju si ± 5 mPa·s, nireti lati t? aw?n idanwo ile-iwosan ni 2026.

Youdaoplaceholder0 Ipari: Nigbati Im?ye molikula pade Gut Ecology ?

Irin-ajo im?-jinl? ti polydextrose j? itan-ak??l? ipadab? lati “?ja-?ja ile-i??” si “?l?r? ilolupo oporoku”. O s? fun wa pe aw?n a?ey?ri otit? ni ilera nigbagbogbo ma nwaye lati is?d?tun ti o jinl? ati is?d?tun-aala ti ipil? ti ?r? naa. G??g?? bí ?l??bùn Nobel ti Jennifer Doudna ti s?, “??k?? ìjìnl?? ??dá alààyè ń k?? wa pé a lè fún àw?n molecule ‘a(chǎn)gbara láti ronú’.” Ninu Iyika im?-?r? ti ilera ifun, polydextrose le j? aaye ib?r? - nigbati di? sii “aw?n ohun elo ti oye” darap? m? ogun naa, eniyan yoo baj? ?e a?ey?ri aw?n ?na atako kong? lodi si aw?n arun onibaje.