I-Vitamin E (I-Vitamin E) iyiqembu lamavithamini ancibilikayo aqukethe i-α, β, γ, δ-tocopherol ne-tocotrienol. Kungumsoco obalulekile umzimba ongakwazi ukuwenza ngokwawo, futhi ungenye yama-antioxidants abaluleke kakhulu i-12.
Isakhiwo samakhemikhali siqukethe izindandatho ze-benzopyrane namaketanga aseceleni e-hydrophobic, anikeza ukungena kwe-lipid membrane 67.
izakhiwo zomzimba namakhemikhali

I-Solubility : i-soluble in fat, i-ethanol nezinye izincibilikisi eziphilayo, ezingancibiliki emanzini 12.
Ukuzinza : ukumelana nokushisa (≤200 ° C) nezimo ezine-acidic kodwa zizwela i-alkali, umoya-mpilo, imisebe ye-UV nama-ion ensimbi (Fe3 + + /Cu2 +). Ukuthosa kuwonakalisa kakhulu umsebenzi

Okokuqala, i-antioxidant synergistic mechanism yamahhala ye-radical scavenging circulatory system

I-Vitamin E, njenge-antioxidant e-fat-soluble, ikhetha ukukhetha ama-radicals mahhala e-lipid ku-membrane yeseli, kuyilapho i-vitamin C, njenge-antioxidant encibilika emanzini, inciphisa futhi ivuselele i-vitamin E ene-oxidized (i-tocopherol free radicals), yenza umjikelezo oqhubekayo we-antioxidant 17.
Ukuhlola kubonisa ukuthi inhlanganisela yalokhu okubili ingathuthukisa ukusebenza kahle kwe-antioxidant ngezikhathi ze-3, i-molecule eyodwa i-vitamin E ingakwazi ukususa ngokuqhubekayo ama-radicals wamahhala we-4, i-vitamin C ngokusebenzisa indlela yokuvuselela ukuze ikhulise isikhathi sayo sokusebenza i-78.

Inethiwekhi ye-Interphase Defense

I-Vitamin E iqinisa i-lipid bilayer ye-membrane yeseli futhi ivimbele ukusabela kweketango le-lipid peroxidation. I-Vitamin C ikhipha ama-radicals mahhala ancibilikayo emanzini ku-cytoplasmic matrix ukuze akhe uhlelo lokuvikela i-lipid-water biphasic 13.

Okwesibili, i-immune system bidirectional activation effect ithuthukisa ukungatheleleki kwangaphakathi: I-Vitamin C ikhuthaza i-neutrophil chemotaxis, i-vitamin E ithuthukisa umsebenzi wamaseli e-NK, futhi inhlanganisela inciphisa izehlakalo zokutheleleka komgudu wokuphefumula ngama-32% 15.
ilawula ukuzivikela okuguquguqukayo : i-synergistically ivuselela ukwanda kwe-T lymphocyte, ithuthukisa ukusebenza kahle kokukhiqizwa kwamasosha omzimba ngama-28%, futhi ibe nomthelela omuhle ekuphenduleni komgomo 57.

Okwesithathu, indlela yokungenelela yezempilo yesikhumba

Ukuvikela ukuthwebula izithombe

I-Vitamin E ivimbela i-sepiperoxidation eyenziwe yi-UV futhi uvithamini C uvimba umsebenzi we-tyrosinase, i-enzyme eyinhloko ekuhlanganiseni kwe-melanin, futhi inhlanganisela yehlisa izinga le-erythematosis yesikhumba ngama-54% 24.

Ukulawulwa kwe-collagen metabolism

I-Vitamin C yenza i-prolyl hydroxylase isebenze ukuze ikhuthaze ukuhlanganiswa kwe-collagen, futhi uvithamini E wehlisa umsebenzi we-collagenase ukuvimbela ukuwohloka. Izivivinyo zemitholampilo zibonise ukuthi ukunwebeka kwesikhumba kuthuthukiswa ngo-23% futhi ukujula kwemibimbi kuncipha ngo-19% 34.

4. Imodi yokuhlanganyela yokuvikela inhliziyo nemithambo yegazi
Ukungenelela kwe-atherosclerosis : I-Vitamin E ivimbela i-oxidation ye-low-density lipoprotein (LDL) kanye ne-vitamin C elungisa i-vascular endothelium eyonakele kuhlanganiswe ne-18% engozini ephansi yezehlakalo zenhliziyo ne-15.
ukuthuthukiswa kwe-microcirculation : uvithamini E wehlisa ukuhlangana kweplatelet okungavamile, uvithamini C uthuthukisa ukuqina kwe-capillary, futhi unenani lokuvikela ngokuhlanganyela kanye nokwelashwa kwe-retinopathy yesifo sikashukela 58.

5. Izici ze-Metabolic cooperative optimization
Ukulawulwa kwe-iron metabolism : I-Vitamin C izonciphisa i-iron e-trivalent ibe yi-bivalent iron, ithuthukise izinga lokumunca izikhathi ezingu-2-3; I-Vitamin E ivikela ukuqina kolwelwesi lwe-erythrocyte futhi yehlise nengozi ye-hemolysis 57.
Ibhalansi ye-cholesterol : I-Vitamin E ivimbela i-HMG-CoA reductase ukunciphisa ukuhlanganiswa kwe-cholesterol, uvithamini C ukhuthaza ukuchithwa kwe-bile acid, futhi ngokuhlangene wehlisa amazinga e-cholesterol ephelele ngo-12% -15%