I-Beta-hydroxy-beta-methylbutyric acid (HMB) itholakala kakhulu ezithelweni ezisawolintshi, imifino ethile efana ne-broccoli, imidumba efana ne-alfalfa, nezinhlanzi ezithile kanye nezilwane zasolwandle. I-Beta-hydroxy-beta-methylbutyric acid (HMB), njenge-metabolite ye-leucine, iboniswe ukwandisa ukuhlanganiswa kwemisipha, ukunciphisa ukuwohloka kwemisipha, futhi kunemiphumela ephikisana nokuvuvukala. Ukuguqulwa kwe-HMB kusawoti oqinile we-β-hydroxy-β-methylbutyrate calcium (HMB-CA) sekusetshenziswe kakhulu ekudleni kwezemidlalo nokunye ukudla, okungadlala indima ekhethekile yokudla okunomsoco:

I-1, esetshenziselwa ukukhuthaza ukukhula kwemisipha, ukuthuthukisa ukungatheleleki, ukunciphisa izinga le-cholesterol kanye ne-low-density lipoprotein (LDL) emzimbeni ukunciphisa ukuvela kwesifo senhliziyo kanye nesifo senhliziyo, kodwa futhi nokuthuthukisa ikhono lokulungiswa kwe-nitrogen yomuntu, ukugcina amazinga amaprotheni emzimbeni;

2, ingafakwa eziphuzweni, ubisi nemikhiqizo yobisi, imikhiqizo kakhokho, ushokoledi kanye nemikhiqizo kashokoledi, uswidi, izinto ezibhakwayo, ukudla okukhethekile okudliwayo, inani elinconyiwe lisengu-≤3 g / ngosuku; 3, I-United States Food and Drug Administration GRAS ukuqashelwa, ububanzi bokusetshenziswa kokudla okunomsoco wezokwelapha nokudla okukhethekile. Ngokusho kweThebula 2 kanye neThebula lesi-3 le-China "Imithetho Ejwayelekile Yokudla Okunomsoco Wezemidlalo Yezinga Likazwelonke Lokuphepha Kokudla" (GB 24154-2015), i-1-3 g / ngosuku ingangezwa emikhiqizweni yokudla kwezemidlalo yejubane namandla.