Imisipha yakho iyakushiya njengoba ukhula! Uma ungawakhi umsipha, uzoba namathuba amaningi okuthola isisindo kunabanye, futhi ukuhlala isikhathi eside kuzodala "umbuthano wokubhukuda." Abantu asebekhulile ngeminyaka, njengabazali nogogo nomkhulu, bavame ukuba nomuzwa wokuthi izitho zomzimba zabo zibuthakathaka futhi bakuthola kunzima ukukhuphuka izitebhisi, okubangelwa nokuncipha kwe-calcium ngenxa yokukhula, okubangela izinkinga zamathambo. Kwatholakala ukuthi i-HMBCa ingazixazulula lezi zinkinga. Esixukuni sokufaneleka, singahlinzeka ngesengezo sokudla okunempilo kwemisipha. Kubantu abaneminyaka ephakathi kanye nasebekhulile bangasiza ekuvimbeleni i-osteoporosis, ukubola kwemisipha; I-HMBCa yaziwa nangokuthi "umenzi wemisipha".

Ngaphezu kwalokho, izifundo zezokwelapha zithole ukuthi i-HMBCa ingasiza futhi abantu abanezimila ukubuyisela impilo yemisipha.

1. Indlela yokusebenza nokuphepha kwe-HMBCa

I-Beta-hydroxy-beta-methylbutyric acid (HMB) iyi-metabolite ye-leucine. Ama-amino acid e-branched chain akha amaprotheni angaphezu kwama-30% emisipha, phakathi kwawo i-leucine okuwukuphela kwe-amino acid engalawula ukuguqulwa kwamaprotheni emisipha yohlaka lwamathambo nenhliziyo, engalawula ukwakheka kwemisipha, ivimbele ukuwohloka kwamaprotheni kanye nokululama kokulimala kwezemidlalo.

I-HMBCa ingenye yezindlela ezivamile ezihambisanayo ze-HMB, futhi iyinsiza entsha yezinto ezingavuthiwe ezigunyazwe uMnyango Wezempilo e-China, futhi ukuphepha kwayo kuhlolisiswe kabanzi. Ezifundweni zabantu, ukuthathwa kwansuku zonke kwe-6gHMB akutholakalanga ukuthi kunomphumela ku-cholesterol, i-hemoglobin, amangqamuzana amhlophe egazi, amazinga kashukela egazini, isibindi nokusebenza kwezinso ngemva kwenyanga engu-1 yokusetshenziswa. U-Baier wafunda ukusetshenziswa kwansuku zonke kwe-2 kuya ku-3gCaHMB ngengxube ye-amino acid kubantu asebekhulile, futhi akukho zinguquko ezitholakele egazini lesibindi nezinso negazi legazi ngemuva konyaka ongu-1 wokusetshenziswa.

2. Ukusetshenziswa kwe-HMBCa ekudleni kwezilwane

Ucwaningo luye lwabonisa ukuthi ukusetshenziswa kwe-HMBCa ezinkukhu zenyama kungathuthukisa ukusebenza kokukhula futhi kwandise okuqukethwe kwenyama engenamafutha, ukuze kwandiswe ngempumelelo isivuno senyama, kanye nokwengezwa kwe-HMBCa okuphakelayo kungathuthukisa ukukhula kwemfuyo nezinkukhu futhi kuthuthukise ukuzivikela kwezilwane.

UGuo Junqing et al. ukhethe izimbuzi zoboya obumhlophe be-Inner Mongolia ezinempilo futhi wengeza ukugxila okuhlukile kwe-HMBCa kanye ne-leucine ekudleni okuyisisekelo. Imiphumela yabonisa ukuthi ukungezwa kwe-leucine ne-HMBCa ekudleni kungakhuphula okuqukethwe kwe-serum lysozyme, kwandise okuqukethwe kwe-serum immunoglobulin futhi kuthuthukise ukusebenza komzimba wokuzivikela komzimba.

3. Ukusetshenziswa kwe-HMBCa kwezokudla kwezemidlalo

Ucwaningo luye lwabonisa ukuthi ukudla i-calcium beta-hydroxy-beta-butyrate ngemva kokuzivocavoca akukwazi nje ukusheshisa ukulungiswa kwezicubu zemisipha, kodwa futhi kukhuthaze ukukhula kwevolumu yemisipha, ukwandisa ukukhuthazela, nokuthuthukisa amandla.

Ngo-Okthoba 2013, i-International Society of Sports Nutrition (ISSN) yenze ukuhlaziya okuqinile nokunemininingwane yezincwadi ze-HMB njengesengezo sokudla okunempilo futhi yenza isitatimende esilandelayo. ① Ngokulimala kohlaka lwamathambo okuvivinya umzimba kubantu abaqeqeshiwe nabangaqeqeshiwe, i-HMB inganciphisa ukulimala kwemisipha futhi ikhuthaze ukululama. Abasubathi bazohlomula ekuziqeqesheni nasekufakeni izintambo nge-HMB. ③ Faka i-HMB ngaphambi kokuzivocavoca amaviki angu-2 ukuze uthole imiphumela ehamba phambili. Ukuzivocavoca okufanele kubantu abaqeqeshiwe noma abangaqeqeshiwe, okuhambisana nesengezo sansuku zonke se-38mg/kg·BMI ye-HMB, kungakhuthaza ukukhula kwemisipha yamathambo futhi kwandise amandla emisipha namandla. Imiphumela ye-HMB ihlanganisa ukuwohloka kwamaprotheni okuncishisiwe kanye nokukhula kwamaprotheni.

4. Ukusetshenziswa kwe-HMBca ekudleni kwefomula ngezinjongo ezikhethekile zezokwelapha

Ukudla okwenziwa ngefomula ngezinjongo zokwelapha ezikhethekile kunokubaluleka okubalulekile emtholampilo ekulungiseni ukungalingani kwezinqubo ze-metabolic, ukunciphisa izinkinga ezinjengokutheleleka, ukuthuthukisa umphumela wezindlela ezihlukahlukene zokwelapha, ukukhuthaza ukululama, ngaleyo ndlela kufinyeze ukuhlala esibhedlela nokuthuthukisa izinga lempilo yeziguli.