Amalunga ayisisekelo sesakhiwo esixhumanisa amathambo amabili ukuze aqedele ukunyakaza okuguquguqukayo. Imisipha ayihlinzeki nje kuphela amandla okunyakaza, kodwa futhi imisipha kanye nemisipha ehlanganiswe eduze kwamalunga iyisisekelo esibalulekile sesakhiwo sokuqinisekisa ukuzinza kwamalunga. Imisipha ingakwazi ukulawula ngokuqinile ukuzinza kwamalunga njengensimbi nosimende.I-HMB-Ca(β-hydroxy-β-methylbutyrate), ethuthukisa ukukhula kwemisipha, isithandwa esisha emkhakheni wezithako zokudla okunomsoco we-osteoarthritis.

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I-Beta-hydroxy-beta-methylbutyric acid (HMB) itholakala kakhulu ezithelweni ezisawolintshi, imifino ethile efana ne-broccoli, imidumba efana ne-alfalfa, nezinhlanzi ezithile kanye nezilwane zasolwandle. I-Beta-hydroxy-beta-methylbutyric acid (HMB), njenge-metabolite ye-leucine, iboniswe ukwandisa ukuhlanganiswa kwemisipha, ukunciphisa ukuwohloka kwemisipha, futhi kunemiphumela ephikisana nokuvuvukala. Ukuguqulwa kwe-HMB ibe usawoti oqinile we-β-hydroxy-β-methylbutyrate calcium (I-HMB-CA) isetshenziswe kabanzi ekudleni kwezemidlalo nokunye ukudla, okungadlala indima ekhethekile yokudla okunomsoco:

I-1, esetshenziselwa ukukhuthaza ukukhula kwemisipha, ukuthuthukisa ukungatheleleki, ukunciphisa izinga le-cholesterol kanye ne-low-density lipoprotein (LDL) emzimbeni ukunciphisa ukuvela kwesifo senhliziyo kanye nesifo senhliziyo, kodwa futhi nokuthuthukisa ikhono lokulungiswa kwe-nitrogen yomuntu, ukugcina amazinga amaprotheni emzimbeni;
2, ingafakwa eziphuzweni, ubisi nemikhiqizo yobisi, imikhiqizo kakhokho, ushokoledi kanye nemikhiqizo kashokoledi, uswidi, izinto ezibhakwayo, ukudla okukhethekile okudliwayo, inani elinconyiwe lisengu-≤3 g / ngosuku; 3, I-United States Food and Drug Administration GRAS ukuqashelwa, ububanzi bokusetshenziswa kokudla okunomsoco wezokwelapha nokudla okukhethekile. Ngokusho kweThebula 2 kanye neThebula lesi-3 le-China "Imithetho Ejwayelekile Yokudla Okunomsoco Wezemidlalo Yezinga Likazwelonke Lokuphepha Kokudla" (GB 24154-2015), i-1-3 g / ngosuku ingangezwa emikhiqizweni yokudla kwezemidlalo yejubane namandla.