Umphumela wokulwa nokuvuvukala we-vitamin E utholakala ikakhulukazi ngezindlela eziningi ze-synergistic, futhi indlela ethize imi kanje:

1. Vimbela indlela yokubonisa ukuvuvukala
I-Vitamin E yandisa amazinga e-sphingolipid, isebenze i-protein e-anti-inflammatory A20, ivimbela i-TNF - α - i-actised ye-NF - κ B indlela yokusayina, ngaleyo ndlela ivimbele ukubonakaliswa kwe-NF - κ B amaprotheni futhi inciphise ukushuba kwempendulo yokuvuvukala.
I-NF - κ B iyisici esiyinhloko sokuloba esilawula ama-cytokines ane-pro-inflammatory, futhi ukuvimbela umsebenzi wawo kunganciphisa ukukhiqizwa kwabalamuli abavuthayo.
2. Ukunciphisa ama-radicals mahhala futhi unciphise ukucindezeleka okwenziwe nge-oxidative
I-Vitamin E ivimbela ngokungaqondile izimpendulo ezivuthayo ezihlobene nokucindezeleka kwe-oxidative ngokususa ama-radicals mahhala kanye nokunciphisa ukulimala kwamaselula okubangelwa ukucindezeleka okwenziwe nge-oxidative.
3. Vimbela ngokuqondile ukukhululwa kwabaxhumanisi abavuthayo
Vimbela ukukhululwa kwama-pro-inflammatory kanye nama-chemokines ngamaseli avuthayo njengama-neutrophils nama-macrophages, futhi unciphise izimpendulo zokuvuvukala kwezicubu zendawo.
Yehlisa ukukhiqizwa kwemikhiqizo ye-lipid peroxidation (efana ne-malondialdehyde) futhi ugweme ukugqugquzelwa kwayo kokukhulisa isignali yokuvuvukala.
4. Ukulawula ukusebenza kwamangqamuzana omzimba
Thuthukisa umsebenzi wokulwa nokuvuvukala kwamangqamuzana omzimba omzimba, njengokuvimbela amaseli e-T no-B asebenza ngokweqile, nokulinganisa izimpendulo zamasosha omzimba.
Vikela ukwakheka kwe-membrane yamangqamuzana omzimba omzimba, ugcine umsebenzi wawo ojwayelekile, futhi uvimbele ukusabela okungalawuleki kokuvuvukala.
Izicelo eziqondile zemiphumela elwa nokuvuvukala
Ukuvuvukala kwesikhumba: Ukukhulula ububomvu besikhumba nokuvuvukala okubangelwa imisebe ye-ultraviolet noma izisusa zangaphandle, vimbela umsebenzi we-tyrosinase, futhi unciphise ingozi yokuba nebala.
Isifo sokuvuvukala esingamahlalakhona: singasiza ekudambiseni isifo samathambo, isifo sokuqina kwemithambo yegazi kanye nezinye izimpawu zesifo esingamahlalakhona ezihlobene nokuvuvukala