Itiye ngesinye seziphuzo ezidume kakhulu emhlabeni, ikakhulukazi eChina. Itiye e-China akuyona nje isiphuzo, kodwa futhi uphawu lwendlela yokuphila namasiko.

Ukuphuza itiye kuthathwa njengomkhuba wempilo enempilo ngoba itiye liqukethe izinhlobonhlobo zezinhlanganisela ezizuzisayo, njenge-catechin, i-tea polyphenols kanye ne-caffeine. Ucwaningo oluningi luye lwabonisa ukuthi i-tea extract ingavimbela umdlavuza, yelule impilo, inciphise ingozi yomfutho wegazi ophakeme, isifo sikashukela, isifo senhliziyo nokunye.

Isifo sesibindi esinamafutha angenaso utshwala (NAFLD) siwuhlobo oluvame kakhulu lwesifo sesibindi esingapheli e-China, esineziguli ezingaphezu kwezigidi ezingu-150. Njengamanje, azikho izidakamizwa ezigunyazwe ukwelapha isifo sesibindi esinamafutha angenalo utshwala, futhi iziguli zingangenelela kuphela ngezinguquko zokudla nokuzivocavoca. Ngakho-ke, kunesidingo esiphuthumayo sokuthuthukisa amasu amasha okwelapha.

Muva nje, Abacwaningi abavela e-China Medical University bashicilele iphepha elinesihloko esithi "I-Epigallocatechin gallate inciphisa isifo sesibindi esinamafutha angenaso utshwala" kumagazini we-Clinical Nutrition ngokusebenzisa ukuvinjelwa kwenkulumo nomsebenzi we-Dipeptide kinase 4 ".

Lolu cwaningo luqinisekisile ngokuhlolwa okulawulwa ngokungahleliwe emitholampilo, ukuhlolwa kwezilwane kanye nokuhlolwa kwe-in vitro ukuthi i-EGCG, isithako esiyinhloko se-bioactive etiyeni eliluhlaza, isiza ukuthuthukisa isibindi esinamafutha, i-ECGC ivimbela ukuqoqwa kwe-lipid, ivimbela ukuvuvukala, ilawula i-lipid metabolism, ivimbele ukulimala kwesibindi, futhi ithuthukise i-non-alcoholic fat fat expression4 inhibiting of (DPP4).

I-Dipeptide kinase 4 (DPP4), i-protease ehlukanisa uhla lwama-substrates ebusweni beseli, ibilokhu iqoqa ubufakazi bokuthi i-DPP4 idlala indima ekuthuthukiseni i-NAFLD, neziguli ze-NAFLD ezibonisa umsebenzi ophezulu we-plasma DPP4 uma kuqhathaniswa nabantu abanempilo.

Kulolu cwaningo, abacwaningi bahlaziye ukusebenza kahle okungenzeka kwe-EGCG ezigulini ezine-NAFLD ngokusebenzisa izivivinyo ezilawulwa ngokungahleliwe emitholampilo, babona ukuthuthukiswa kwe-EGCG esibindini samagundane angamamodeli ngokusebenzisa ukuhlolwa kwemodeli yezilwane, futhi bahlaziya indlela yokuthuthukiswa kwe-EGCG ku-NAFLD ngokusebenzisa ukuhlolwa kwe-in vitro.

Esivivinyweni somtholampilo esilawulwa ngokungahleliwe esibandakanya abahlanganyeli be-15 abane-NAFLD, i-EGCG idliwe amaphilisi etiye polyphenol, futhi idatha yesibindi yalinganiswa ekuqaleni, amasonto angu-12, namaviki angu-24.

Imiphumela yathola ukuthi iziguli zazinokuqukethwe kwamafutha esibindi okuphansi kakhulu ngemva kwamasonto angu-24 okwelashwa kwe-EGCG uma kuqhathaniswa nesisekelo, futhi iziguli ezimbili zazinokukhululwa kwesibindi esinamafutha ngemva kokuphela kwesikhathi sokwelashwa kweviki le-24. Ngaphezu kwalokho, umjikelezo wokhalo lweziguli kanye namazinga e-cholesterol ephelele nawo ehle kakhulu ngemva kwamasonto angama-24.

Ukuhlaziywa kubonise ukuthi ngemva kwamasonto angu-24 okwelashwa kwe-EGCG, amazinga e-AST ancishiswa futhi amazinga e-DPP4 nawo ancishiswa.

Ukuhlaziywa kokusebenza kwezinso kubonise ukuthi amazinga e-creatinine e-serum namanani esilinganiso sokuhlunga kwe-glomerular ahlala ebangeni elivamile, okubonisa ukuthi i-EGCG inephrofayili yokuphepha enhle.