Emkhakheni womsebenzi wokudla okunomsoco,vitamin Ekufana ne-maverick "ikhanda lomkhonto." Iningiivithaminiimikhuba isebenza njenge-coenzyme ekuphenduleni kwamakhemikhali, idlala indima eyisizayo, futhi i-vitamin E iyingqayizivele, inamandla ayo aqinile okuvikela impilo yomuntu. Vitamin E kungokwalaboamafutha ancibilikayoUmndeni wamavithamini futhi iphuma ku-benzodihydropyrane enesakhiwo esifanayo nomsebenzi webhayoloji, ikakhulukazi ohlanganisa i-tocopherol ne-tocotrienol. Iqembu ngalinye lihlukaniswe izingxenye ezine, i-α, β, γ kanye no-δ, ngokomehluko wesikhundla se-methyl eringini ye-benzopyrane, ingqikithi yezinhlobo ezingu-8, futhi lawa ma-isomer anamandla okulwa ne-antioxidant. Ama-radicals amahhala ayikilasi lama-molecule angazinzile anamakhemikhali aphezulu kakhulu akhiqizwa ohlelweni lwe-metabolism yomzimba. Ukukhanya kwe-Ultraviolet, ukungcoliswa kwemvelo nezinye izici zangaphandle kungabangela ukukhiqizwa kwama-radicals mahhala, futhi i-mitochondria iyindawo yokukhiqiza ama-radical mahhala lapho amangqamuzana enza i-aerobic metabolism ukuze anikeze amandla. Ama-radicals amahhala amaningi adala ingcindezi ye-oxidative, ehlasela ama-macromolecule ebhayoloji afana ne-lipids, amaprotheni kanye ne-DNA ngaphakathi kwamaseli, okuholela ekulimaleni kwe-oxidative. Ngezikhathi ezibucayi, i-vitamin E incike esakhiweni sayo se-phenolic hydroxyl ukuze inikeze ama-athomu e-hydrogen ukuze asabele ngama-radicals mahhala, anciphise ama-radicals mahhala, aphazamise ukusabela kweketanga le-oxidative, futhi ngaleyo ndlela avikele amaseli.

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I-fat-solubility kavithamini E yenza ukuthi isatshalaliswe ngokukhethekile ezindaweni ezinothe ngama-lipids, njengama-cell membranes nama-lipoprotein. Kulezi zindawo, ivimbela ngokuqinile i-lipid peroxidation. Lapho ama-radicals mahhala ehlasela amafutha e-polyunsaturatedama-asidi, okubangela ukusabela kweketanga le-lipid peroxidation elilimaza ulwelwesi lwamangqamuzana nama-lipoprotein, uvithamini E angamisa ukusabela ezigabeni zokuqala nezokudlulisela, avikele i-lipids emathunjini, egazini, ezicutshini kanye nolwelwesi lwamangqamuzana. Esimisweni senhliziyo nemithambo yegazi,vitamin Einciphisa ukukhiqizwa kwe-oxidized low-density lipoprotein ngomphumela we-antioxidant, inciphisa ukulimala kwayo kumaseli e-vascular endothelial, bese ivimbela ukwakheka nokuthuthukiswa kwe-atherosclerotic plaque. Ngesikhathi esifanayo, uvithamini E angalawula futhi ukwanda nokufuduka kwamangqamuzana emisipha abushelelezi emithanjeni ukuze kugcinwe ukushuba okujwayelekile nokunwebeka kwemithambo yegazi. I-Vitamin E nayo idlala indima ebalulekile ekulawuleni amasosha omzimba. Ikhuthaza ukwanda nokuhlukaniswa kwamangqamuzana omzimba omzimba afana ne-T no-B lymphocyte, ithuthukisa ukusebenzisana phakathi kwamaseli, futhi ithuthukise ukusabela komzimba. Ngesikhathi esifanayo, ibamba iqhaza ekulawulweni kokudluliselwa kwesignali ye-immune cell, ithinta ukugcinwa nokubonakaliswa kwama-cytokines, futhi ilawula ukuphendula komzimba. Imithombo yemvelo eyinhloko kavithamini E ihlanganisa amafutha emifino, amantongomane, imbewu, nemifino enamahlamvu eluhlaza. Kule mithombo, amafutha emifino anothe kakhulu kuvithamini E, ikakhulukazi osesimweni se-alpha-tocopherol. Ngaphezu kwalokho, kunezithako ze-multivitamin E emakethe, okuhlanganisa i-softgel, amaphilisi ahlafunwayo nama-creams, afanele izidingo zamaqembu ahlukene abantu. Ngokusekelwe ekusetshenzisweni kwereferensi yomsoco wokudla, ukuthathwa okunconyiwe kukavithamini E kubantu abadala kungu-15 mg ngosuku (kukalwa ngokulingana kwe-alpha-tocopherol). Kodwa-ke, idatha yangempela yocwaningo ibonisa ukuthi isilinganiso senani likavithamini E elidliwa abantu abadala ngokudla kwabo kwansuku zonke ngokuvamile lingaphansi kuka-10 mg. Olunye ucwaningo luye lwabonisa ukuthi ekwelashweni kwe-adjuvant yezifo ezithile njengokulibaziseka ukuguga nokuthuthukisa ukukhubazeka kwengqondo, ukufaka ama-200-800 mg we-vitamin E nsuku zonke kungase kube nomphumela othile. Ngokuvamile, uvithamini E ophuzwayo uphephile, kodwa ukuthathwa okuphezulu kwesikhathi eside (ngaphezu kuka-1,000 mg ngosuku) kungase kwandise amathuba okusabela okungekuhle njengengozi yokopha. Ngakho-ke, lapho usebenzisa izithasiselo ze-vitamin E, kubalulekile ukulandela izeluleko zochwepheshe ukuze uqinisekise ukuphepha nokuhluzeka kwesengezo.