I-Vitamin B12 ibizwa nangokuthi i-Hydroxycobalamin

Xhumana nathi

imininingwane yomkhiqizo

Isingeniso

IHydroxycobalamin (ohcbl, noma i-B12a) iwuhlobo lwemvelo lukavithamini B12, noma elinye lamakilasi kavithamini B12. Kuyilungu eliyisisekelo leqembu le-cobalamine. Amabhaktheriya amaningi akhiqiza amavithamini akhiqiza uvithamini B12 ngendlela ye-hydroxycobalamin. IHydroxycobalamin ibomvu ngokumnyama. I-Vitamin B12 emzimbeni womuntu ngokuvamile ayitholakali ngesimo se-hydroxycobalamin. Nokho, kubantu, i-hydroxycobalamin iguqulwa kalula ibe uhlobo oluwusizo lwe-coenzyme kavithamini B12. Umkhiqizo wokwelapha we-hydroxycobalamin umjovo wawo oyinyumba, osetshenziselwa ukwelapha ukuntuleka kwamavithamini kanye nobuthi be-cyanide (ngoba uhambisana nama-ion e-cyanide). I-Hydroxycobalamin nayo isetshenziswe njenge-scavenger.

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Umsebenzi

Njengamanje, kunezinhlobo ezine zevithamini B12 emakethe ye-API yomhlaba. Ziyi-hydroxycobalamin, i-mecobalamin, i-cyanobalamin ne-cobalamin adenosine. Lokhu kungenxa yokuthi i-ion ephakathi ku-molecule ye-B12 inamaqembu ahlukene asebenzayo, ngakho ibizwa ngokuthi amagama ahlukene. IHydroxycobalamin ibizwa nge-hydroxycobalamin ngoba i-ion emaphakathi ye-B12 ixhunywe neqembu le-hydroxyl. Phakathi kwama-molecule e-B12, i-hydroxycobalamin inokuncibilika okungcono kakhulu kwamanzi kanye ne-metabolism ehamba kancane emchameni, owaziwa nangokuthi i-cobalamin esebenza isikhathi eside. Nakuba izinga lokumunca lingenakuqhathaniswa nele-cyanocobalan ne-Mecobalamin, ukugxila kwayo esweni kuphezulu kakhulu, okungakhulula kakhulu ukukhathala okubukwayo futhi kondle i-optic nerve. Ngakho-ke, inomphumela othile wokwelapha ku-amblyopia ebangelwa ubuthi. Ngaphezu kwalokho, i-hydroxycobalamin ingahlangana ngokushesha ne-cyanide yamahhala ukuze yakhe i-cyanobalamin engenabuthi esixazululweni samanzi, ngakho-ke omunye umphumela wayo wokwelapha uyikhambi lobuthi be-cyanide.

Ukucaciswa komkhiqizo

Izinto	Amazinga	Imiphumela
Ukuhlaziywa ngokomzimba namakhemikhali
Ukubukeka	Impushana ephaphathekile ibe nsundu i-hygroscopicity	Iyahambisana
Ukuhlonza	Yiba nokumunca okuphezulu ku-361±1nm,550±2nm	Iyahambisana
Ukulahlekelwa ekomisweni	≤12%	9.0%
Isivivinyo	09.0%-1.3%	1%
Izinsalela ekushiseni	≤0.1%	0.06%
Insimbi Enzima
I-Arsenic(As)	≤0.1mg/kg	Iyahambisana
Ukuhola(Pb)	≤1mg/kg	Iyahambisana
Ukuhlolwa kweMicrobiological
Inani Lepuleti Eliphelele	≤1000cfu/g	Iyahambisana
Isikhunta nemvubelo	≤100cfu/g	Iyahambisana
I-Coliform	Okubi	Okubi
E.coli	Okubi	Okubi
I-Salmonella	Okubi	Okubi
I-Staphylococcus	Okubi	Okubi
Ulwazi oluvamile
Iphakheji: 25kg / ibhokisi
Isitoreji: Umkhiqizo kufanele ugcinwe endaweni eyomile nepholile, futhi uvimbele umswakama, ukukhanya kwelanga, ukuqubuka kwezinambuzane, ukungcoliswa kwezinto eziyingozi kanye nomunye umonakalo.
Impilo yeshelufu	3 iminyaka